Plasma ferritin and type 2 diabetes mellitus: A critical review

I. Eshed, A. Elis, M. Lishner

Research output: Contribution to journalArticlepeer-review


Multiple factors appear to be involved in the pathogenesis of type 2 (non insulin dependent) diabetes mellitus (DM). One of these factors may be iron overload. This critical review summarizes the major studies on the link between type 2 DM, insulin resistance, glycemic control, diabetic complications and hyperferritinemia. Although some studies suggested that plasma ferritin concentration is positively correlated with insulin resistance and with the risk of acquiring type 2 DM, substantial iron overload is not a typical feature of DM. There is no correlation between plasma ferritin level and glycemic control or diabetic microangiopathic complications.

Original languageEnglish
Pages (from-to)91-97
Number of pages7
JournalEndocrine Research
Issue number1-2
StatePublished - 2001
Externally publishedYes


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