Placental location and obstetrical-neonatal outcomes: A retrospective study

Neta Doctory, Asaf Romano, Inbal Navon, Shiri Barbash-Hazan, Ron Bardin, Eran Hadar*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Objective: To explore the potential association of lateral placentation with pregnancy outcome. Methods: The database of a tertiary medical center was searched for women who gave birth to a singleton neonate from 2012 to 2020 for whom placental location was documented during antepartum sonographic examination. Clinical data were compared between patients with a central (anterior/posterior/fundal) or lateral placenta using standard statistics. The primary outcome measure was neonatal birthweight, and secondary outcome measures were pregnancy complications and mode of delivery. Results: The cohort included 12 306 women: 11 608 (94%) with a central placenta and 698 (5.6%) with a lateral placenta. The lateral placenta group had higher rates (P < 0.05) of prior and current cesarean delivery, assisted delivery, and preterm birth. On multivariate regression analyses, placental location (adjusted odds ratio [aOR], 1.36; 95% confidence interval [CI], 1.11–1.66) and maternal age (aOR, 1.02; 95% CI, 1.01–1.03) were associated with risk of preterm birth. Lateral placenta (aOR, 1.22; 95% CI, 1.02–1.47), maternal age (aOR, 1.07; 95% CI, 1.06–1.08), parity (aOR, 0.32; 95% CI, 0.28–0.35), and prior cesarean delivery (aOR, 12.00; 95% CI, 10.60–13.60) were associated with risk of current cesarean delivery. Conclusion: The findings suggest that lateral placentation may pose a risk of preterm birth and cesarean delivery compared with central placentation.

Original languageEnglish
Pages (from-to)641-645
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Issue number2
StatePublished - Feb 2023


  • birth weight
  • cesarean delivery
  • location
  • neonatal outcome
  • placenta
  • pregnancy outcome
  • preterm birth


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