Placental isoferritin patterns during first-trimester intrauterine gestation

Ron Maymon, Jacob Bar, Reuvit Halperin, Ian Bukovsky, Chaya Moroz*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


In this study, serum placental ferritin (PLF) levels were measured among 33 pregnant women with normal, singleton, ongoing first-trimester gestations and compared with 22 nonbleeding, missed and 14 incomplete abortions. Diagnoses were based on clinical, sonographic, endocrinologic and histo-pathologic criteria. At admission and before uterine evacuation of the pregnancy products, venous blood was collected from the groups for PLF determination. The mean ± SD serum PLF levels were 18 ± 14, 21 ± 37, and 3.9 ± 6.2 U/ml in normal gestations, missed and incomplete abortions, respectively. Significant differences in PLF levels were found among normal pregnancies and incomplete abortions (p < 0.05), whereas borderline significance was found in the missed abortion group (p = 0.53). No correlation was found between serum βhCG and PLF for the various pregnancy groups. Low PLF levels in pathologic gestation may reflect abnormal trophoblastic activity. Whether these play a causal role or are the casual outcome of pathologic gestation should be the subject of further evaluation.

Original languageEnglish
Pages (from-to)271-273
Number of pages3
JournalGynecologic and Obstetric Investigation
Issue number4
StatePublished - 1 Jan 1996


  • First-trimester pregnancy
  • Incomplete abortion
  • Missed abortion
  • Placental isoferritin


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