Placental insufficiency as a possible cause of low maternal serum human chorionic gonadotropin and low maternal serum unconjugated estriol levels in triploidy

Moshe Fejgin, Aliza Amiel, Shmuel Goldberger, Inbal Barnes, Tamar Zer, Gertrude Kohn

Research output: Contribution to journalArticlepeer-review

Abstract

We report three cases in which triploidy (69,XXX) was detected by amniocentesis performed for very low maternal serum human chorionic gonadotropin levels. All three cases also had low maternal serum unconjugated estriol levels. We suggest placental insufficiency as the cause of the very low human chorionic gonadotropin because of histologic observations and because a known marker for placental insufficiency, estriol, was also very low.

Original languageEnglish
Pages (from-to)766-767
Number of pages2
JournalAmerican Journal of Obstetrics and Gynecology
Volume167
Issue number3
DOIs
StatePublished - 1992

Keywords

  • Amniocentesis
  • low maternal serum unconjugated estriol
  • maternal serum human chorionic gonadotropin
  • placental insufficiency
  • triploidy

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