Pineal germinoma with unilateral blindness seeding of germinoma cells in optic nerve sheath

Riri S. Manor*, Jacob Bar-Ziv, Rina Tadmor, Avi Eisbruch, Gideon Rechavi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

A 13-year-old boy presented with blindness and loss of the papillomacular bundle in the left eye, bilateral papilledema sparing the area of axonal loss, and Parinaud’s syndrome. Computerized tomography (CT) revealed an enlarged kinked left optic nerve and enlarged optic canal as well as a tumor in the pineal area producing hydrocephalus. Magnetic resonance (MR) scans showed multiple spinal metastases. The histological diagnosis was germinoma. On completion of four courses of chemotherapy with cis-platin, vinblastine, and bleomycin, repeated CT of orbita and MR imaging of the spine demonstrated the disappearance of the tumor surrounding the left optic nerve and of the spinal metastases. This is believed to be the first case report of seeding of germinoma into the perioptic arachnoid space.

Original languageEnglish
Pages (from-to)239-243
Number of pages5
JournalJournal of Clinical Neuro-Ophthalmology
Volume10
Issue number4
StatePublished - Dec 1990

Keywords

  • Blindness
  • Pinealisik
  • Subarachnoid space of optic nerve sheath

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