Photosensitivity due to isotretinoin: a possible allergic mechanism

Boaz Amichai*, Marcelo H. Grunwald, Ella Livni, Sima Halevy

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Photosensitivity is listed as a side effect to isotretinoin, but reports in the literature are contradictory. Only a few cases of photosensitivity, phototoxicity and photoallergy, have been reported. We describe herein a case of a photosensitivity due to isotretinoin. The possible role of an allergic mechanism in this reaction has been suggested by a positive mast‐cell degranulation (MCD) test toward the drug.

Original languageEnglish
Pages (from-to)27-30
Number of pages4
JournalJournal of the European Academy of Dermatology and Venereology
Issue number1
StatePublished - Mar 1993
Externally publishedYes


  • Isotretinoin
  • Mast‐cell degranulation (MCD) text
  • Photosensitivity


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