Photoacoustic thermal diffusion flowmetry in tissue-mimicking phantoms

Adi Sheinfeld, Avishay Eyal

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Photoacoustic Thermal Diffusion Flowmetry (PA-TDF) utilizes photothermal heating and photoacoustic temperature monitoring to measure the tissue heat clearance time constants from which blood velocity can be inferred. We extended our study of PA-TDF to tissue-mimicking phantoms with vessels at various diameters, configurations and depths and experimentally verified the relations between the estimated time constants and the vessels and the illuminating beam dimensions. We also demonstrated, for the first time, depth-resolved PA-TDF measurement using tone-burst photoacoustic excitation. The excitation utilized two fiber-coupled 830nm laser diodes, one induced slow temperature oscillations and the other induced the PA excitation.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2013
DOIs
StatePublished - 2013
EventPhotons Plus Ultrasound: Imaging and Sensing 2013 - San Francisco, CA, United States
Duration: 3 Feb 20135 Feb 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8581
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2013
Country/TerritoryUnited States
CitySan Francisco, CA
Period3/02/135/02/13

Keywords

  • Flow measurement
  • Laser diodes
  • Photoacoustic imaging
  • Photothermal excitation
  • Thermal Diffusion Flowmetry

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