TY - JOUR
T1 - Phenotypic modulation of fibroblasts in massive ovarian edema
T2 - An immunohistochemical study of three cases
AU - Lifschitz-Mercer, Beatriz
AU - Gabbiani, G.
AU - Gal, R.
AU - Siegal, A.
AU - Czernobilsky, B.
PY - 1996
Y1 - 1996
N2 - An immunohistochemical study of three cases of massive ovarian edema revealed coexpression of vimentin, total actins, alpha-smooth muscle actin, desmin and low molecular weight cytokeratins in the stromal spindle cells composing the edematous ovarian tissue. In addition these stromal cells expressed smooth muscle myosin which is a marker for terminal smooth muscle differentiation. This remarkable fibroblastic cell plasticity in massive ovarian edema may represent yet another example of fibroblastic modulations occurring under the influence of microenvironmental stress factors.
AB - An immunohistochemical study of three cases of massive ovarian edema revealed coexpression of vimentin, total actins, alpha-smooth muscle actin, desmin and low molecular weight cytokeratins in the stromal spindle cells composing the edematous ovarian tissue. In addition these stromal cells expressed smooth muscle myosin which is a marker for terminal smooth muscle differentiation. This remarkable fibroblastic cell plasticity in massive ovarian edema may represent yet another example of fibroblastic modulations occurring under the influence of microenvironmental stress factors.
KW - Case reports differentiation
KW - Massive ovarian edema
KW - Modulation fibroblasts
KW - Muscle
UR - http://www.scopus.com/inward/record.url?scp=0030253397&partnerID=8YFLogxK
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AN - SCOPUS:0030253397
VL - 28
SP - 435
EP - 440
JO - Journal of Submicroscopic Cytology
JF - Journal of Submicroscopic Cytology
SN - 1122-9497
IS - 4
ER -