@article{f9ec17f18ad94bf58164796583537af8,
title = "Phenotypic heterogeneity in a bacteriophage population only appears as stress-induced mutagenesis",
abstract = "Stress-induced mutagenesis has been studied in cancer cells, yeast, bacteria, and archaea, but not in viruses. In a recent publication, we present a bacteriophage model showing an apparent stress-induced mutagenesis. We show that the stress does not drive the mutagenesis, but only selects the fittest mutants. The mechanism underlying the observed phenomenon is a phenotypic heterogeneity that resembles persistence of the viral population. The new findings, the background for the ongoing debate on stress-induced mutagenesis, and the phenotypic heterogeneity underlying a novel phage infection strategy are discussed in this short manuscript.",
keywords = "Cryptic growth, Darwin, Lamarck, Natural selection, Phage resistance",
author = "Ido Yosef and Rotem Edgar and Udi Qimron",
note = "Publisher Copyright: {\textcopyright} 2016, Springer-Verlag Berlin Heidelberg.",
year = "2016",
month = nov,
day = "1",
doi = "10.1007/s00294-016-0606-2",
language = "אנגלית",
volume = "62",
pages = "771--773",
journal = "Current Genetics",
issn = "0172-8083",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "4",
}