Phenothiazine treatment and respiratory distress syndrome in a child

Gideon Eshel; Marian Usher; Joseph Barr; Roni Heggesh; Eliezer Lahat

doi:10.3109/15563659409000450

Phenothiazine treatment and respiratory distress syndrome in a child

Gideon Eshel^*, Marian Usher, Joseph Barr, Roni Heggesh, Eliezer Lahat

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

An 11-year-old boy who was treated with a relatively high dose of methotrimeprazine meleate (Levemepromazine) a phenothiazine antipsychotic drug, was admitted to the pediatric intensive care unit suffering from respiratory distress syndrome. He required intensive treatment and support for 13 days. The persistent effects of methotrimeprazine meleate on various organs are typical of the prolonged biological action of the phenothiazine metabolites. The association of phenothiazine overdose and respiratory distress syndrome merits consideration.

Original language	English
Pages (from-to)	191-197
Number of pages	7
Journal	Clinical Toxicology
Volume	32
Issue number	2
DOIs	https://doi.org/10.3109/15563659409000450
State	Published - 1994
Externally published	Yes

Keywords

Adult respiratory distress syndrome
Antipsychotic drugs
Clothiaprine
Phenothiazines

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10.3109/15563659409000450

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AB - An 11-year-old boy who was treated with a relatively high dose of methotrimeprazine meleate (Levemepromazine) a phenothiazine antipsychotic drug, was admitted to the pediatric intensive care unit suffering from respiratory distress syndrome. He required intensive treatment and support for 13 days. The persistent effects of methotrimeprazine meleate on various organs are typical of the prolonged biological action of the phenothiazine metabolites. The association of phenothiazine overdose and respiratory distress syndrome merits consideration.

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Phenothiazine treatment and respiratory distress syndrome in a child

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