Phenothiazine treatment and respiratory distress syndrome in a child

Gideon Eshel*, Marian Usher, Joseph Barr, Roni Heggesh, Eliezer Lahat

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


An 11-year-old boy who was treated with a relatively high dose of methotrimeprazine meleate (Levemepromazine) a phenothiazine antipsychotic drug, was admitted to the pediatric intensive care unit suffering from respiratory distress syndrome. He required intensive treatment and support for 13 days. The persistent effects of methotrimeprazine meleate on various organs are typical of the prolonged biological action of the phenothiazine metabolites. The association of phenothiazine overdose and respiratory distress syndrome merits consideration.

Original languageEnglish
Pages (from-to)191-197
Number of pages7
JournalClinical Toxicology
Issue number2
StatePublished - 1994
Externally publishedYes


  • Adult respiratory distress syndrome
  • Antipsychotic drugs
  • Clothiaprine
  • Phenothiazines


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