Phenobarbital in Dubin Johnson syndrome (Hebrew)

C. Merdler, S. Felner, M. Burke, M. Shani, I. Lurie

Research output: Contribution to journalArticlepeer-review


8 Jaundiced patients with Dubin Johnson syndrome were treated with oral phenobarbital, 0.1 g 3 times daily for 2 wk. Serum bilirubin and bromsulfalein clearance decreased (p < 0.005) while other parameters of liver function were not altered significantly. Phenobarbital appears to act by enhancing biliary excretion of organic anions.

Original languageEnglish
Pages (from-to)466-468+495
Issue number10
StatePublished - 1976


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