TY - JOUR
T1 - PET-CT imaging of combined brachial and lumbosacral neurolymphomatosis
AU - Kanter, Pazit
AU - Zeidman, Aliza
AU - Streifler, Jonathan
AU - Marmelstein, Victor
AU - Even-Sapir, Einat
AU - Metser, Ur
AU - Stein, Gideon Y.
AU - Cohen, Amos M.
PY - 2005/1
Y1 - 2005/1
N2 - Neurolymphomatosis is a rare manifestation of progressive non-Hodgkin's lymphoma. A 44-yr-old man with diffuse large B-cell lymphoma presented with unilateral progressive peripheral sensorimotor neuropathy after the 7th cycle of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) therapy. No pathology in the nervous system was evident by computerized tomography (CT), magnetic resonance imaging (MRI) of the head, spinal axis and plexuses and by repeated analysis of cerebrospinal fluid. However, the hybrid modality of positron emission tomography (PET) of fluorinated deoxyglucose (FDG) combined with CT scan (PET-CT) showed unilateral involvement of both the brachial and lumbosacral nervous plexuses. A complete recovery of neurological manifestations and normalization of PET-CT followed intensive chemotherapy with autologous stem cell transplantation. The diagnosis and localization of neurolymphomatosis may be supported by PET-CT imaging.
AB - Neurolymphomatosis is a rare manifestation of progressive non-Hodgkin's lymphoma. A 44-yr-old man with diffuse large B-cell lymphoma presented with unilateral progressive peripheral sensorimotor neuropathy after the 7th cycle of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) therapy. No pathology in the nervous system was evident by computerized tomography (CT), magnetic resonance imaging (MRI) of the head, spinal axis and plexuses and by repeated analysis of cerebrospinal fluid. However, the hybrid modality of positron emission tomography (PET) of fluorinated deoxyglucose (FDG) combined with CT scan (PET-CT) showed unilateral involvement of both the brachial and lumbosacral nervous plexuses. A complete recovery of neurological manifestations and normalization of PET-CT followed intensive chemotherapy with autologous stem cell transplantation. The diagnosis and localization of neurolymphomatosis may be supported by PET-CT imaging.
KW - Aggressive lymphoma
KW - Brachial and lumbosacral plexopathy
KW - Fluorine-18 fluorodeoxyglucose
KW - Neurolymphomatosis
KW - Positron emission tomography
UR - http://www.scopus.com/inward/record.url?scp=12444309430&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0609.2004.00369.x
DO - 10.1111/j.1600-0609.2004.00369.x
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AN - SCOPUS:12444309430
SN - 0902-4441
VL - 74
SP - 66
EP - 69
JO - European Journal of Haematology
JF - European Journal of Haematology
IS - 1
ER -
