Personalized participatory medicine: Sharing knowledge and uncertainty

David Gurwitz*, Jeantine E. Lunshof

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Informing patients about risks and benefits of alternative treatment options and choosing between them is becoming a bigger challenge as knowledge about the relationship between the individual's genetic profile and the efficacy and safety of available medications accumulates. Putting personalized medicine into practice requires new modes of information sharing and decision making by patient and physician. This is illustrated by a case study on treatment choices of breast cancer patients following genotyping for CYP2D6, recently published in Genome Medicine

Original languageEnglish
Article number69
JournalGenome Medicine
Issue number10
StatePublished - 27 Oct 2011


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