The purpose of the study was to attempt a discrimination between stages of cervical premalignancy in terms of the four Eysenckian dimensions. It consisted of a quasi-prospective design applied to the presumed continuum of cervical premalignancy. The Ss were 88 women addressed by a physician or self-addressed for Pap smear examinations. Prior to the Pap smear they completed a demographic questionnaire and the Eysenck Personality Questionnaire providing scores of extraversion (E), neuroticism (N), psychoticism (P) and lie (L). By the Pap smear results there were four groups of women: healthy, suffering from vaginal or cervical inflammations, suffering from human papillomaviruses (HPV), and suffering from dysplasias or cervical intraepithelial neoplasms (CIN). ANOVA and discriminant analyses showed that the Eysenckian dimensions discriminated correctly with above chance significance between the groups, mainly between the healthy and inflammatory, on the one hand, and the HPV and CIN, on the other hand (on the basis of N and E scores), and less well between the healthy and inflammatory (on the basis of L scores), and least between the HPV and CIN (on the basis of P scores). As expected, in the healthy and inflammatory groups as compared with the HPV and CIN groups, N and P scores were higher whereas E and L scores were lower. The results indicate the correspondence between physiological and psychological characteristics and suggest especially the alternating relation between neuroticism and physical pathology.