Persistent right umbilical vein: Incidence and significance

I. Wolman, I. Gull, G. Fait, R. Amster, M. J. Kupferminc, J. B. Lessing, A. J. Jaffa

Research output: Contribution to journalReview articlepeer-review


Objectives: To conduct a prospective evaluation of the incidence and neonatal outcome of fetuses with persistent right umbilical vein. This condition had traditionally been considered to be extremely rare and to be associated with a very poor neonatal prognosis, but later evidence has raised some doubts about the veracity of these contentions. Methods: Between August 1995 and November 1998, 8950 low-risk patients were prospectively evaluated at two medical centers. The sonographic diagnosis of a persistent right umbilical vein was made in a transverse section of the fetal abdomen when the portal vein was curved toward the stomach, and the fetal gall bladder was located medially to the umbilical vein. Results: Persistent right umbilical vein was detected in 17 fetuses during the study. Four of them had additional malformations, of which three had been detected antenatally. Conclusions: We established that the incidence of persistent right umbilical vein in a low-risk population is 1:526. We believe that the sonographic finding of this anomaly is an indication for conducting targeted fetal sonography and echocardiography. When the persistent right umbilical vein is connected to the portal system and other anomalies are ruled out, the prognosis can generally be expected to be favorable.

Original languageEnglish
Pages (from-to)562-564
Number of pages3
JournalUltrasound in Obstetrics and Gynecology
Issue number6
StatePublished - 2002


  • Incidence
  • Outcome
  • Persistent right umbilical vein


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