TY - JOUR
T1 - Persistent nonketotic hyperglycemia as a grave prognostic sign in head-injured patients.
AU - Merguerian, P. A.
AU - Perel, A.
AU - Wald, U.
AU - Feinsod, M.
AU - Cotev, S.
PY - 1981/12
Y1 - 1981/12
N2 - The authors studied 86 consecutive patients admitted to the ICU after severe head trauma. Of these, 19 nondiabetic patients developed persistent nonketotic hyperglycemia (NKH), defined as plasma glucose greater than 270 mg/dl (15 mM/L), 1.7 +/- 1.1 (SD) days after injury. When NKH occurred, all patients were in very deep coma (Glasgow Coma Scale score 3), and when intracranial pressure (ICP) was measured (12 patients), its mean value was 59.8 +/- 20.4 mm Hg. Although 11 of 19 patients had associated diabetes insipidus (DI), NKH was not related to increased fluid and glucose loading. All patients with NKH died (mean time of survival after NKH was 2.1 +/- 1.4 days) in contrast to a 17.1% early mortality rate in patients with severe head injury without NKH. The authors could not show a direct correlation between the height of ICP and the level of blood glucose.
AB - The authors studied 86 consecutive patients admitted to the ICU after severe head trauma. Of these, 19 nondiabetic patients developed persistent nonketotic hyperglycemia (NKH), defined as plasma glucose greater than 270 mg/dl (15 mM/L), 1.7 +/- 1.1 (SD) days after injury. When NKH occurred, all patients were in very deep coma (Glasgow Coma Scale score 3), and when intracranial pressure (ICP) was measured (12 patients), its mean value was 59.8 +/- 20.4 mm Hg. Although 11 of 19 patients had associated diabetes insipidus (DI), NKH was not related to increased fluid and glucose loading. All patients with NKH died (mean time of survival after NKH was 2.1 +/- 1.4 days) in contrast to a 17.1% early mortality rate in patients with severe head injury without NKH. The authors could not show a direct correlation between the height of ICP and the level of blood glucose.
UR - http://www.scopus.com/inward/record.url?scp=0019762037&partnerID=8YFLogxK
U2 - 10.1097/00003246-198112000-00007
DO - 10.1097/00003246-198112000-00007
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 7318455
AN - SCOPUS:0019762037
SN - 0090-3493
VL - 9
SP - 838
EP - 840
JO - Critical Care Medicine
JF - Critical Care Medicine
IS - 12
ER -
