TY - JOUR
T1 - Persistence of obstructive sleep apnea syndrome in children after adenotonsillectomy
AU - Tauman, Riva
AU - Gulliver, Tanya E.
AU - Krishna, Jyoti
AU - Montgomery-Downs, Hawley E.
AU - O'Brien, Louise M.
AU - Ivanenko, Anna
AU - Gozal, David
N1 - Funding Information:
This study was supported by the National Institutes of Health (grant HL-65270), The Children’s Foundation Endowment for Sleep Research, and the Commonwealth of Kentucky Challenge for Excellence Trust Fund. RT was supported by an Ohio Valley American Heart Association Fellowship.
PY - 2006/12
Y1 - 2006/12
N2 - Objective: To investigate the relative contribution of various risk factors to the surgical outcome of adenotonsillectomy for obstructive sleep apnea syndrome in children. Study design: Children (n = 110; mean age, 6.4 ± 3.9 years) underwent two polysomnographic evaluations before and after adenotonsillectomy. In addition, 22 control children were studied. History for allergy and family history of sleep-disordered breathing was taken before each polysomnographic evaluation. Results: Significant changes in sleep stage percentages and sleep fragmentation were found in the postsurgery study compared with the presurgery study; 25% of the children had apnea/hypopnea index (AHI) ≤1, 46% had AHI >1 and <5, and 29% had AHI ≥5 in the postsurgery study. The frequency of subjects with AHI ≤1 after surgery was significantly lower among obese subjects (P < .05). Comparison between the children who had AHI ≤1 after surgery and 22 control children showed complete normalization of sleep architecture after surgery. Conclusions: Adenotonsillectomy yields improvements in respiratory abnormalities in children with obstructive sleep apnea syndrome. Complete normalization occurs in only 25% of the patients. Obesity and AHI at diagnosis are the major determinant for surgical outcome. When normalization of respiratory measures occurs after surgery, normalization of sleep architecture will also ensue.
AB - Objective: To investigate the relative contribution of various risk factors to the surgical outcome of adenotonsillectomy for obstructive sleep apnea syndrome in children. Study design: Children (n = 110; mean age, 6.4 ± 3.9 years) underwent two polysomnographic evaluations before and after adenotonsillectomy. In addition, 22 control children were studied. History for allergy and family history of sleep-disordered breathing was taken before each polysomnographic evaluation. Results: Significant changes in sleep stage percentages and sleep fragmentation were found in the postsurgery study compared with the presurgery study; 25% of the children had apnea/hypopnea index (AHI) ≤1, 46% had AHI >1 and <5, and 29% had AHI ≥5 in the postsurgery study. The frequency of subjects with AHI ≤1 after surgery was significantly lower among obese subjects (P < .05). Comparison between the children who had AHI ≤1 after surgery and 22 control children showed complete normalization of sleep architecture after surgery. Conclusions: Adenotonsillectomy yields improvements in respiratory abnormalities in children with obstructive sleep apnea syndrome. Complete normalization occurs in only 25% of the patients. Obesity and AHI at diagnosis are the major determinant for surgical outcome. When normalization of respiratory measures occurs after surgery, normalization of sleep architecture will also ensue.
UR - http://www.scopus.com/inward/record.url?scp=33751335040&partnerID=8YFLogxK
U2 - 10.1016/j.jpeds.2006.08.067
DO - 10.1016/j.jpeds.2006.08.067
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 17137896
AN - SCOPUS:33751335040
SN - 0022-3476
VL - 149
SP - 803
EP - 808
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 6
ER -
