The present study is an attempt to assess the state of central opiate systems in the same animals at 4 months of age. In this study naloxone did not suppress feeding as effectively in the group treated with naltrexone early in life as it did in the control group. These data and the fact that morphine analgesia developed sooner in the naltrexone treated animals suggest that animals treated neonatally with an opiate antagonism may have more, or more efficient, opiate receptors as a result of this early antagonism.
|Number of pages||3|
|Journal||Proceedings of the Western Pharmacology Society|
|State||Published - 1978|