@article{37323475d73c46f68d8964ff23e71306,
title = "Peripheral benzodiazepine binding sites on platelet membranes are increased during diazepam treatment of anxious patients",
abstract = "Reduced (24%) [3H]PK 11195 binding capacity to platelet membranes was observed in anxious patients in comparison to age- and sex-matched normal controls. Four weeks of diazepam treatment induced elevation (69%) in the maximal number of binding sites, and 1 week of drug withdrawal resulted in a slight decrease (16%) in 'peripheral' benzodiazepine binding sites as compared to their level during treatment.",
keywords = "Diazepam, Generalized anxiety disorder, Peripheral benzodiazepine binding sites, [H]PK 11195",
author = "Ronit Weizman and Zehava Tanne and Michel Granek and Leon Karp and Mira Golomb and Sam Tyano and Moshe Gavish",
note = "Funding Information: This work was supported by a grant from the Israel Mimstry of Health Tins paper is m partial fulfillment of the requirements for the M.Sc. degree of Z Tanne at the Techmon-Israel Institute of Technology. We thank Mass Ruth Singer for typing the manuscript.",
year = "1987",
month = jun,
day = "19",
doi = "10.1016/0014-2999(87)90447-X",
language = "אנגלית",
volume = "138",
pages = "289--292",
journal = "European Journal of Pharmacology",
issn = "0014-2999",
publisher = "Elsevier B.V.",
number = "2",
}
