Peripapillary fluid: Obvious and not so obvious!

Supriya Arora, Dinah Zur, Claudio Iovino, Jay Chhablani*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Intraretinal or subretinal fluid in the peripapillary area can be clinically visualized in conditions such as peripapillary choroidal neovascularization, optic disc pit maculopathy, and optic nerve head tumors and granulomas. Optical coherence tomography (OCT) helps to visualize peripapillary fluid in many other chorioretinal conditions such as peripapillary pachychoroid syndrome, posterior uveitis, central retinal vein occlusion, malignant hypertension, hypotonic maculopathy as well as neuro-ophthalmological conditions such as glaucoma, microcystic macular edema and disc edema due papilledema, non-arteritic anterior ischemic optic neuropathy, neuroretinitis, and diabetic papillopathy. Often, the differential diagnosis of peripapillary fluid is a bit tricky and may lead to misdiagnosis and improper management. We describe a diagnostic algorithm for peripapillary fluid on OCT and outline the salient features and management of these conditions.

Original languageEnglish
JournalSurvey of Ophthalmology
StateAccepted/In press - 2023


  • Choroidal neovascularization
  • Disc edema
  • Peripapillary fluid
  • Peripapillary pachychoroid syndrome
  • Peripapillary retinoschisis


Dive into the research topics of 'Peripapillary fluid: Obvious and not so obvious!'. Together they form a unique fingerprint.

Cite this