Perinatal outcome in women with severe pregnancy complications and multiple thrombophilias

Michael J. Kupferminc; Elyahu Rimon; Jessica Ascher-Landsberg; Joseph B. Lessing; Ariel Many

doi:10.1515/JPM.2004.042

Perinatal outcome in women with severe pregnancy complications and multiple thrombophilias

Michael J. Kupferminc^*, Elyahu Rimon, Jessica Ascher-Landsberg, Joseph B. Lessing, Ariel Many

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Hypercoagulability leading to placental thrombosis has been implicated in severe pregnancy complications. We compared the perinatal outcome in women with severe preeclampsia, intrauterine growth retardation (IUGR) and severe abruptio placentae and multiple acquired and inherited thrombophilias (study group, n = 22) to matched women with similar complications and single thrombophilia (control group, n = 22). Gestational age at delivery and birth weight were significantly lower in the study group compared to the control group (p < 0.01) and among the study women with severe preeclampsia and IUGR. Severe pregnancy complications may occur earlier during pregnancy and more seriously affect perinatal outcome in women with multiple thrombophilias.

Original language	English
Pages (from-to)	225-227
Number of pages	3
Journal	Journal of Perinatal Medicine
Volume	32
Issue number	3
DOIs	https://doi.org/10.1515/JPM.2004.042
State	Published - 2004

Keywords

Abruptio placentae
IUGR
Preeclampsia
Pregnancy complication
Thrombophilia

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title = "Perinatal outcome in women with severe pregnancy complications and multiple thrombophilias",

abstract = "Hypercoagulability leading to placental thrombosis has been implicated in severe pregnancy complications. We compared the perinatal outcome in women with severe preeclampsia, intrauterine growth retardation (IUGR) and severe abruptio placentae and multiple acquired and inherited thrombophilias (study group, n = 22) to matched women with similar complications and single thrombophilia (control group, n = 22). Gestational age at delivery and birth weight were significantly lower in the study group compared to the control group (p < 0.01) and among the study women with severe preeclampsia and IUGR. Severe pregnancy complications may occur earlier during pregnancy and more seriously affect perinatal outcome in women with multiple thrombophilias.",

keywords = "Abruptio placentae, IUGR, Preeclampsia, Pregnancy complication, Thrombophilia",

author = "Kupferminc, {Michael J.} and Elyahu Rimon and Jessica Ascher-Landsberg and Lessing, {Joseph B.} and Ariel Many",

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T1 - Perinatal outcome in women with severe pregnancy complications and multiple thrombophilias

AU - Kupferminc, Michael J.

AU - Rimon, Elyahu

AU - Ascher-Landsberg, Jessica

AU - Lessing, Joseph B.

AU - Many, Ariel

PY - 2004

Y1 - 2004

N2 - Hypercoagulability leading to placental thrombosis has been implicated in severe pregnancy complications. We compared the perinatal outcome in women with severe preeclampsia, intrauterine growth retardation (IUGR) and severe abruptio placentae and multiple acquired and inherited thrombophilias (study group, n = 22) to matched women with similar complications and single thrombophilia (control group, n = 22). Gestational age at delivery and birth weight were significantly lower in the study group compared to the control group (p < 0.01) and among the study women with severe preeclampsia and IUGR. Severe pregnancy complications may occur earlier during pregnancy and more seriously affect perinatal outcome in women with multiple thrombophilias.

AB - Hypercoagulability leading to placental thrombosis has been implicated in severe pregnancy complications. We compared the perinatal outcome in women with severe preeclampsia, intrauterine growth retardation (IUGR) and severe abruptio placentae and multiple acquired and inherited thrombophilias (study group, n = 22) to matched women with similar complications and single thrombophilia (control group, n = 22). Gestational age at delivery and birth weight were significantly lower in the study group compared to the control group (p < 0.01) and among the study women with severe preeclampsia and IUGR. Severe pregnancy complications may occur earlier during pregnancy and more seriously affect perinatal outcome in women with multiple thrombophilias.

KW - Abruptio placentae

KW - IUGR

KW - Preeclampsia

KW - Pregnancy complication

KW - Thrombophilia

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Perinatal outcome in women with severe pregnancy complications and multiple thrombophilias

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