Performance of the Linox implantable cardioverter defibrillator leads: A single-center experience

Ibrahim Marai*, Anat Milman, Eyal Nof, Osnat Gurevitz, David Barlev, Igor Lipchenca, Sharona Bachar, Michael Glikson, Roy Beinart

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: An early failure of Biotronik Linox implantable cardioverter defibrillator (ICD) leads has been reported from several centers. Aim: To compare the performance of Linox ICD leads with different other ICD leads as a report of the Sheba Medical Center experience. Methods: All patients who had implantation of Linox ICD leads between 2007 and 2016 were included in this study. ICD lead failure was defined as low- or high-voltage impedance; failure to capture, sense, or defibrillate; or the presence of nonphysiological signals not due to external interference. The survival probability of Linox leads was determined and compared to Medtronic Sprint Quattro ICD leads. Results: A total of 340 patients (age 64.4 ± 1.8 years) were included in this analysis. They were followed up to 105 months (mean 45.7 ± 7, median 44 (Interquartile range (IQR) 26-63) months). Twelve patients (3.5%) met the criteria for lead failure within 61.2 ± 22.9 months (median 66.5 [IQR 48–85 months]) post implantation. Noise with inappropriate ventricular arrhythmias detection, with or without therapy, was seen in 10 patients (83%). High pacing thresholds and high impedances were detected in two patients (17%). The survival probability of Linox leads at 60 months (97.3%) was similar to the survival probability of Sprint Quattro leads (98.2%) (P =.58). Nevertheless, the survival probability at 105 months was much lower (81% vs 97%, Linox ICD lead and Sprint Quattro lead, respectively, P =.0039). Conclusion: Linox ICD leads have higher late failure rates compared to Sprint Quattro leads. These findings need to be confirmed in larger scale studies.

Original languageEnglish
Pages (from-to)1524-1528
Number of pages5
JournalPACE - Pacing and Clinical Electrophysiology
Issue number12
StatePublished - 1 Dec 2019


  • Linox
  • Sprint Quattro
  • lead failure


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