Penetration of clindamycin, cefoxitin, and metronidazole into pelvic peritoneal fluid of women undergoing diagnostic laparoscopy

S. A. Berger*, M. Kupferminc, J. B. Lessing, A. Gorea, I. Gull, M. R. Peyser

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A single dose of clindamycin, cefoxitin, or metronidazole was administered to each of 30 women. The mean concentration of cefoxitin in pelvic fluid at 1 h exceeded those of the other two drugs (P < 0.007). Cefoxitin concentrations were inferior to those of the other drugs when compared with the published MIC for 90% of Bacteroides fragilis strains.

Original languageEnglish
Pages (from-to)376-377
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Volume34
Issue number2
DOIs
StatePublished - 1990
Externally publishedYes

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