Pemphigus vulgaris in pregnancy: A case report and review of literature

Ofer Fainaru, Roy Mashiach, Michael Kupferminc, Michael Shenhav, David Pauzner, Joseph B. Lessing

Research output: Contribution to journalArticlepeer-review


Pemphigus vulgaris (PV) is an uncommon, immune-mediated bullous dermatosis, which, during its active phase, has been associated with infertility. Pemphigus vulgaris during pregnancy is exceedingly rare - only 26 cases with immunopathological confirmation have been reported. The disease may be associated with adverse neonatal outcome, including prematurity and fetal death. Transient skin lesions may occasionally appear in the neonate. We report a patient who conceived during the active phase of PV, required high doses of corticosteroids to control the disease, and was delivered of a pre-term, appropriate-for-gestational age newborn.

Original languageEnglish
Pages (from-to)1195-1197
Number of pages3
JournalHuman Reproduction
Issue number5
StatePublished - 2000


  • Pemphigus vulgaris
  • Pregnancy


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