Pemphigus vulgaris in adolescence. A case presentation and review of the literature

Meir Gorsky*, Mili Raviv, Eli Raviv

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Pemphigus vulgaris, a chronic autoimmune vesiculobullous disease, affects people in their fifth or sixth decade of life. Involvement in adolescence is rare with only about 30 cases reported in the last 35 years. This article presents a case of adolescent pemphigus vulgaris in a 15-year-old girl with oral and skin lesions. The patient has been free of lesions with a maintenance dosage of 10 mg of prednisine every other day. The mean age of the 31 patients, including our patient, was 14 years. Skin involvement was reported in 87% of patients, oral involvement in 87%, and skin and oral lesions in 81% with oral lesions preceding skin lesions. Early diagnosis of adolescent pemphigus vulgaris is important to eliminate or reduce the severity of further intraoral or extraoral involvement. The term adolescent pemphigus vulgarius is suggested when the onset is between 12 and 18 years of age.

Original languageEnglish
Pages (from-to)620-622
Number of pages3
JournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Volume77
Issue number6
DOIs
StatePublished - Jun 1994

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