Pemphigus following hepatitis B vaccination-coincidence or causality?

Yackov Berkun, Daniel Mimouni, Yehuda Shoenfeld*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Pemphigus is an autoimmune blistering disease caused by autoantibodies against epithelial intercellular components. Its etiology is unknown, and neoplasms, antecedent infections or medications are considered possible triggering factors for the disease in some cases. We describe the first case of pemphigus following a hepatitis B virus vaccination. We suggest that in some cases vaccination may be the triggering factor for pemphigus in genetically predisposed individuals and physicians should be aware of this possible association.

Original languageEnglish
Pages (from-to)117-119
Number of pages3
Issue number2
StatePublished - Mar 2005


  • Autoimmunity
  • HBV vaccine
  • Infections
  • Pemphigus vulgaris
  • Vaccination


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