Pediatric neurologic complications associated with influenza A H1N1

Yuval E. Landau, Galia Grisaru-Soen, Shimon Reif, Aviva Fattal-Valevski

Research output: Contribution to journalArticlepeer-review

Abstract

Influenza is associated with a variety of neurologic complications. Although the epidemiologic and clinical characteristics of influenza A H1N1 were reviewed in depth, only brief descriptions of neurologic complications exist. We describe the neurologic complications of children hospitalized with influenza A H1N1 infection. We undertook a retrospective study of all hospitalized children with laboratory-confirmed influenza A H1N1 infection accompanied by neurologic complications during a 4-month winter period. Their demographics and clinical characteristics of neurologic presentations were reviewed. Fourteen of 74 children (19%) with laboratory-confirmed influenza A H1N1 infection presented with neurologic complications. Eleven (11/14, 79%) were previously healthy, and three exhibited chronic conditions. Ten (10/14, 71%) presented with seizures: six were febrile, and four were nonfebrile. Other complications included transverse myelitis, myositis, expressive aphasia, and syncope. Only the child with transverse myelitis required a course of rehabilitation. Neurologic complications associated with influenza A H1N1 in our patients were relatively mild. Seizures (febrile or nonfebrile) were the most common. However, the possibility of influenza A H1N1 infection should be borne in mind when diagnosing children with neurologic signs during the influenza A H1N1 season.

Original languageEnglish
Pages (from-to)47-51
Number of pages5
JournalPediatric Neurology
Volume44
Issue number1
DOIs
StatePublished - Jan 2011

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