Pediatric Antibiotic Stewardship for Community-Acquired Pneumonia: A Pre–Post Intervention Study

Herman Avner Cohen, Maya Gerstein, Yiska Loewenberg Weisband, Yael Richenberg, Eyal Jacobson, Moriya Cohen, Vered Shkalim Zemer*, Maayan Diti Machnes

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We aimed to investigate the effectiveness of an antibiotic stewardship program (ASP) on antibiotic prescription in children with community-acquired pneumonia (CAP). Antibiotic purchasing data were collected for children aged 3 months to 18 years diagnosed with CAP from November 2016 to April 2017 (pre-intervention period) and from November 2017 to April 2018 (post-intervention period). The intervention was a 1-day seminar for primary care pediatricians on the diagnosis and treatment of CAP in children according to national guidelines. There was a substantial decrease in the use of azithromycin after the intervention. In younger children, there was a 42% decrease, alongside an increased use of amoxicillin (P <.001). In older children, there was a smaller, non-statistically significant decrease in the use of azithromycin (P =.45). Our data demonstrate that the implementation of an ASP was associated with a reduction in the use of broad-spectrum antibiotics and macrolides and increased guideline adherence for the safe treatment of CAP.

Original languageEnglish
Pages (from-to)795-801
Number of pages7
JournalClinical Pediatrics
Issue number11
StatePublished - Nov 2022


  • children
  • community-acquired pneumonia
  • pediatric antibiotic stewardship
  • pediatric community health care centers


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