Abstract
Hypocalcemia (HC) is a frequent complication of neonatal polycythemia (NP): 9.93% in the present study. Its pathogenesis is not clear. We suggest that one of the main pathogenetic explanation of HC in NP is the high level of phosphate significantly different (p < 0.01) than serum phosphate of normal normocalcemic non-polycythemic newborns. The intense postnatal erythrocyte breakdown will increase the serum level of phosphate. This hyperphosphatemia will decrease calcium ion concentration by their combination and bone deposition, a process allowed by inadequate postnatal parathyroid gland response.
Original language | English |
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Pages (from-to) | 49-50 |
Number of pages | 2 |
Journal | Medical Hypotheses |
Volume | 30 |
Issue number | 1 |
DOIs | |
State | Published - Sep 1989 |
Externally published | Yes |