PatchDock and SymmDock: Servers for rigid and symmetric docking

Dina Schneidman-Duhovny, Yuval Inbar, Ruth Nussinov, Haim J. Wolfson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2439 Scopus citations


Here, we describe two freely available web servers for molecular docking. The PatchDock method performs structure prediction of protein-protein and protein-small molecule complexes. The SymmDock method predicts the structure of a homomultimer with cyclic symmetry given the structure of the monomeric unit. The inputs to the servers are either protein PDB codes or uploaded protein structures. The services are available at The methods behind the servers are very efficient, allowing large-scale docking experiments.

Original languageEnglish
Pages (from-to)W363-W367
JournalNucleic Acids Research
Issue numberSUPPL. 2
StatePublished - Jul 2005


FundersFunder number
Hermann Minkowski-MINERVA Center for Geometry
Israeli Ministry of Science
National Institutes of HealthNO1-CO-12400
National Cancer InstituteZ01BC010442
Israel Academy of Sciences and Humanities
Israel Science Foundation
Tel Aviv University


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