Paradigmatic cases of pigmented lesions: How to not miss melanoma

Francesca Farnetani*, Alon Scope, Valeria Coco, Stefania Guida, Anna Maria Cesinaro, Simonetta Piana, Ketty Peris, Giovanni Pellacani, Caterina Longo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A large number of cases of melanoma exhibit clinical and dermoscopic clues leading to the correct diagnosis; however, sometimes melanoma can mimic benign melanocytic and non-melanocytic lesions. We present a small series of melanomas in which additional clues provided by confocal microscopy increased the index of suspicion and prompted us to perform an excisional biopsy. Practical rules that are useful in difficult-to-diagnose melanomas are discussed.

Original languageEnglish
Pages (from-to)1433-1437
Number of pages5
JournalJournal of Dermatology
Issue number12
StatePublished - 1 Dec 2016


  • confocal microscopy
  • dermoscopy
  • diagnostic tools
  • melanoma
  • practical rules


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