Ovarian stimulation and in vitro fertilization in women with mature cystic teratomas

Benjamin Caspi, Ariel Weissman, Yaron Zalel, Amihai Barash, Togas Tulandi, Zeev Shoham

Research output: Contribution to journalArticlepeer-review


Objective: To report the results of ovulation induction and in vitro fertilization-embryo transfer (IVF-ET) in patients with ovarian cystic teratomas. Methods: Six women with ultrasonographicaily diagnosed ovarian cystic teratomas (mean diameter 2.4 cm) who presented with infertility underwent IVF-ET (n=4) or ovulation induction (n=2). Serial ultrasound examinations were used to determine the size of the cystic teratomas during therapy and throughout pregnancy. Results: Ovarian stimulation was successful, as evidenced by the serum estradiol concentration on the day of hCG administration (mean in IVF-ET patients, 3558 ± 1319 pg/mL) and the number of oocytes retrieved (10 ± 4.24). Three patients having IVF-ET and both patients having ovulation induction conceived, and six healthy infants were born. Cyst sizes remained unchanged throughout treatment and pregnancy. There were no cyst-related complications during ovulation induction or IVF- ET, or during the entire course of pregnancy, labor, and delivery. Conclusion: The presence of ovarian cystic teratoma should not be considered a contraindication for therapy in women undergoing ovulation induction and IVF-ET.

Original languageEnglish
Pages (from-to)979-981
Number of pages3
JournalObstetrics and Gynecology
Issue number6
StatePublished - Dec 1998


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