Ovarian Hyperstimulation Syndrome Due To Exogenous Gonadotropin Administration

D. Bider, Y. Menashe, G. Oelsner, D. M. Serr, S. Mashiach, Z. Ben‐Rafael*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


During the last decade, 154 patients treated with human menopausal gonadotropin humanchorionic gonadotropin developed hyperstimulation necessitating hospitalization in 201 cycles. Moderate ovarian hyperstimulation occurred in 116 of the patients and severe ovarian hyperstimulation in 34. Sixteen patients underwent operative procedures. Twelve patients underwent puncture of the pleura or abdomen to drain symptomic hydrothorax or ascites, with clinical improvement of the symptoms in all of them. Three patients had coagulation abnormalities, and 1 patient had thromboembolic phenomena. Hyperstimulation seems to be associated with an increased pregnancy rate, since seventy‐five pregnancies (35%) occurred in the study group. Appropriate monitoring can reduce the rate of OHSS but it should be kept in mind that death due to OHSS may occur. 1989 Acta Obstet Gynecol Scand

Original languageEnglish
Pages (from-to)511-514
Number of pages4
JournalActa Obstetricia et Gynecologica Scandinavica
Issue number6
StatePublished - Jan 1989


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