TY - JOUR
T1 - Outcome of "mushroom" pattern femtosecond laser-assisted keratoplasty versus conventional penetrating keratoplasty in patients with keratoconus
AU - Levinger, Eliya
AU - Trivizki, Omer
AU - Levinger, Shmuel
AU - Kremer, Israel
PY - 2014/5
Y1 - 2014/5
N2 - PURPOSE: The aim of this study was to compare the outcomes of "mushroom" femtosecond laser-enabled keratoplasty (M-FLEK) with those of conventional penetrating keratoplasty (PKP) in eyes with keratoconus. The femtosecond laser-enabled "mushroom" pattern keratoplasty technique results in less postoperative astigmatism and higher endothelial cell counts compared with conventional PKP in patients with keratoconus. METHODS: This was a nonrandomized retrospective, single private center clinical study. Between March 2010 and April 2012, 26 eyes underwent M-FLEK and 33 eyes underwent conventional PKP. Data on preoperative and postoperative manifest refraction, uncorrected visual acuity and best-corrected visual acuity (BCVA), endothelial cell counts, vector analysis, and complications were retrieved and analyzed. RESULTS: At 12 months of follow-up, the mean logMAR BCVA was 0.31 ± 0.55 in the M-FLEK group and 0.32 ± 0.21 in the PKP group (P = 0.91). The mean spherical equivalent was similar between the groups. The mean manifest cylinder was significantly lower in the M-FLEK group (-2.84 ± 1.08 diopters) than in the PKP group (-3.93 ± 2.26 diopters; P = 0.03). There was a smaller mean endothelial cell loss in the M-FLEK group compared with the PKP group (32.1% vs 38.7%, respectively, P = 0.17) 1 year postoperatively. The complication rates were similar for both groups. CONCLUSIONS: M-FLEK appears to be a safe procedure that results in less astigmatism and a trend toward higher endothelial cell counts compared with conventional PKP, with similar postoperative BCVA.
AB - PURPOSE: The aim of this study was to compare the outcomes of "mushroom" femtosecond laser-enabled keratoplasty (M-FLEK) with those of conventional penetrating keratoplasty (PKP) in eyes with keratoconus. The femtosecond laser-enabled "mushroom" pattern keratoplasty technique results in less postoperative astigmatism and higher endothelial cell counts compared with conventional PKP in patients with keratoconus. METHODS: This was a nonrandomized retrospective, single private center clinical study. Between March 2010 and April 2012, 26 eyes underwent M-FLEK and 33 eyes underwent conventional PKP. Data on preoperative and postoperative manifest refraction, uncorrected visual acuity and best-corrected visual acuity (BCVA), endothelial cell counts, vector analysis, and complications were retrieved and analyzed. RESULTS: At 12 months of follow-up, the mean logMAR BCVA was 0.31 ± 0.55 in the M-FLEK group and 0.32 ± 0.21 in the PKP group (P = 0.91). The mean spherical equivalent was similar between the groups. The mean manifest cylinder was significantly lower in the M-FLEK group (-2.84 ± 1.08 diopters) than in the PKP group (-3.93 ± 2.26 diopters; P = 0.03). There was a smaller mean endothelial cell loss in the M-FLEK group compared with the PKP group (32.1% vs 38.7%, respectively, P = 0.17) 1 year postoperatively. The complication rates were similar for both groups. CONCLUSIONS: M-FLEK appears to be a safe procedure that results in less astigmatism and a trend toward higher endothelial cell counts compared with conventional PKP, with similar postoperative BCVA.
KW - Astigmatism
KW - Femtosecond
KW - Keratoconus
KW - PKP
UR - http://www.scopus.com/inward/record.url?scp=84897570450&partnerID=8YFLogxK
U2 - 10.1097/ICO.0000000000000080
DO - 10.1097/ICO.0000000000000080
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AN - SCOPUS:84897570450
SN - 0277-3740
VL - 33
SP - 481
EP - 485
JO - Cornea
JF - Cornea
IS - 5
ER -