Outcome measures in spinal cord injury: Recent assessments and recommendations for future directions

M. S. Alexander; K. D. Anderson; F. Biering-Sorensen; A. R. Blight; R. Brannon; T. N. Bryce; G. Creasey; A. Catz; A. Curt; W. Donovan; J. Ditunno; P. Ellaway; N. B. Finnerup; D. E. Graves; B. A. Haynes; A. W. Heinemann; A. B. Jackson; M. V. Johnston; C. Z. Kalpakjian; N. Kleitman; A. Krassioukov; K. Krogh; D. Lammertse; S. Magasi; M. J. Mulcahey; B. Schurch; A. Sherwood; J. D. Steeves; S. Stiens; D. S. Tulsky; H. J.A. Van Hedel; G. Whiteneck

doi:10.1038/sc.2009.18

Outcome measures in spinal cord injury: Recent assessments and recommendations for future directions

M. S. Alexander, K. D. Anderson, F. Biering-Sorensen, A. R. Blight, R. Brannon, T. N. Bryce, G. Creasey, A. Catz, A. Curt, W. Donovan, J. Ditunno, P. Ellaway, N. B. Finnerup, D. E. Graves, B. A. Haynes, A. W. Heinemann, A. B. Jackson, M. V. Johnston, C. Z. Kalpakjian, N. KleitmanA. Krassioukov, K. Krogh, D. Lammertse, S. Magasi, M. J. Mulcahey, B. Schurch, A. Sherwood, J. D. Steeves, S. Stiens, D. S. Tulsky, H. J.A. Van Hedel, G. Whiteneck

Clinical Departments

Research output: Contribution to journal › Review article › peer-review

Abstract

Study design: Review by the spinal cord outcomes partnership endeavor (SCOPE), which is a broad-based international consortium of scientists and clinical researchers representing academic institutions, industry, government agencies, not-for-profit organizations and foundations. Objectives: Assessment of current and evolving tools for evaluating human spinal cord injury (SCI) outcomes for both clinical diagnosis and clinical research studies. Methods: a framework for the appraisal of evidence of metric properties was used to examine outcome tools or tests for accuracy, sensitivity, reliability and validity for human SCI. Results: Imaging, neurological, functional, autonomic, sexual health, bladder/bowel, pain and psychosocial tools were evaluated. Several specific tools for human SCI studies have or are being developed to allow the more accurate determination for a clinically meaningful benefit (improvement in functional outcome or quality of life) being achieved as a result of a therapeutic intervention. Conclusion: Significant progress has been made, but further validation studies are required to identify the most appropriate tools for specific targets in a human SCI study or clinical trial.

Original language	English
Pages (from-to)	582-591
Number of pages	10
Journal	Spinal Cord
Volume	47
Issue number	8
DOIs	https://doi.org/10.1038/sc.2009.18
State	Published - Aug 2009

Keywords

Diagnostic tools
Functional assessment
Outcome tools
Quality of life and community participation
Spinal cord clinical trial targets
Upper and lower limb

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/sc.2009.18

Cite this

Alexander, M. S., Anderson, K. D., Biering-Sorensen, F., Blight, A. R., Brannon, R., Bryce, T. N., Creasey, G., Catz, A., Curt, A., Donovan, W., Ditunno, J., Ellaway, P., Finnerup, N. B., Graves, D. E., Haynes, B. A., Heinemann, A. W., Jackson, A. B., Johnston, M. V., Kalpakjian, C. Z., ... Whiteneck, G. (2009). Outcome measures in spinal cord injury: Recent assessments and recommendations for future directions. Spinal Cord, 47(8), 582-591. https://doi.org/10.1038/sc.2009.18

@article{b38117fc6e604ba1a3da7db3e3175c0d,

title = "Outcome measures in spinal cord injury: Recent assessments and recommendations for future directions",

abstract = "Study design: Review by the spinal cord outcomes partnership endeavor (SCOPE), which is a broad-based international consortium of scientists and clinical researchers representing academic institutions, industry, government agencies, not-for-profit organizations and foundations. Objectives: Assessment of current and evolving tools for evaluating human spinal cord injury (SCI) outcomes for both clinical diagnosis and clinical research studies. Methods: a framework for the appraisal of evidence of metric properties was used to examine outcome tools or tests for accuracy, sensitivity, reliability and validity for human SCI. Results: Imaging, neurological, functional, autonomic, sexual health, bladder/bowel, pain and psychosocial tools were evaluated. Several specific tools for human SCI studies have or are being developed to allow the more accurate determination for a clinically meaningful benefit (improvement in functional outcome or quality of life) being achieved as a result of a therapeutic intervention. Conclusion: Significant progress has been made, but further validation studies are required to identify the most appropriate tools for specific targets in a human SCI study or clinical trial.",

keywords = "Diagnostic tools, Functional assessment, Outcome tools, Quality of life and community participation, Spinal cord clinical trial targets, Upper and lower limb",

author = "Alexander, {M. S.} and Anderson, {K. D.} and F. Biering-Sorensen and Blight, {A. R.} and R. Brannon and Bryce, {T. N.} and G. Creasey and A. Catz and A. Curt and W. Donovan and J. Ditunno and P. Ellaway and Finnerup, {N. B.} and Graves, {D. E.} and Haynes, {B. A.} and Heinemann, {A. W.} and Jackson, {A. B.} and Johnston, {M. V.} and Kalpakjian, {C. Z.} and N. Kleitman and A. Krassioukov and K. Krogh and D. Lammertse and S. Magasi and Mulcahey, {M. J.} and B. Schurch and A. Sherwood and Steeves, {J. D.} and S. Stiens and Tulsky, {D. S.} and {Van Hedel}, {H. J.A.} and G. Whiteneck",

year = "2009",

month = aug,

doi = "10.1038/sc.2009.18",

language = "אנגלית",

volume = "47",

pages = "582--591",

journal = "Spinal Cord",

issn = "1362-4393",

publisher = "Nature Publishing Group",

number = "8",

}

Alexander, MS, Anderson, KD, Biering-Sorensen, F, Blight, AR, Brannon, R, Bryce, TN, Creasey, G, Catz, A, Curt, A, Donovan, W, Ditunno, J, Ellaway, P, Finnerup, NB, Graves, DE, Haynes, BA, Heinemann, AW, Jackson, AB, Johnston, MV, Kalpakjian, CZ, Kleitman, N, Krassioukov, A, Krogh, K, Lammertse, D, Magasi, S, Mulcahey, MJ, Schurch, B, Sherwood, A, Steeves, JD, Stiens, S, Tulsky, DS, Van Hedel, HJA & Whiteneck, G 2009, 'Outcome measures in spinal cord injury: Recent assessments and recommendations for future directions', Spinal Cord, vol. 47, no. 8, pp. 582-591. https://doi.org/10.1038/sc.2009.18

TY - JOUR

T1 - Outcome measures in spinal cord injury

T2 - Recent assessments and recommendations for future directions

AU - Alexander, M. S.

AU - Anderson, K. D.

AU - Biering-Sorensen, F.

AU - Blight, A. R.

AU - Brannon, R.

AU - Bryce, T. N.

AU - Creasey, G.

AU - Catz, A.

AU - Curt, A.

AU - Donovan, W.

AU - Ditunno, J.

AU - Ellaway, P.

AU - Finnerup, N. B.

AU - Graves, D. E.

AU - Haynes, B. A.

AU - Heinemann, A. W.

AU - Jackson, A. B.

AU - Johnston, M. V.

AU - Kalpakjian, C. Z.

AU - Kleitman, N.

AU - Krassioukov, A.

AU - Krogh, K.

AU - Lammertse, D.

AU - Magasi, S.

AU - Mulcahey, M. J.

AU - Schurch, B.

AU - Sherwood, A.

AU - Steeves, J. D.

AU - Stiens, S.

AU - Tulsky, D. S.

AU - Van Hedel, H. J.A.

AU - Whiteneck, G.

PY - 2009/8

Y1 - 2009/8

N2 - Study design: Review by the spinal cord outcomes partnership endeavor (SCOPE), which is a broad-based international consortium of scientists and clinical researchers representing academic institutions, industry, government agencies, not-for-profit organizations and foundations. Objectives: Assessment of current and evolving tools for evaluating human spinal cord injury (SCI) outcomes for both clinical diagnosis and clinical research studies. Methods: a framework for the appraisal of evidence of metric properties was used to examine outcome tools or tests for accuracy, sensitivity, reliability and validity for human SCI. Results: Imaging, neurological, functional, autonomic, sexual health, bladder/bowel, pain and psychosocial tools were evaluated. Several specific tools for human SCI studies have or are being developed to allow the more accurate determination for a clinically meaningful benefit (improvement in functional outcome or quality of life) being achieved as a result of a therapeutic intervention. Conclusion: Significant progress has been made, but further validation studies are required to identify the most appropriate tools for specific targets in a human SCI study or clinical trial.

AB - Study design: Review by the spinal cord outcomes partnership endeavor (SCOPE), which is a broad-based international consortium of scientists and clinical researchers representing academic institutions, industry, government agencies, not-for-profit organizations and foundations. Objectives: Assessment of current and evolving tools for evaluating human spinal cord injury (SCI) outcomes for both clinical diagnosis and clinical research studies. Methods: a framework for the appraisal of evidence of metric properties was used to examine outcome tools or tests for accuracy, sensitivity, reliability and validity for human SCI. Results: Imaging, neurological, functional, autonomic, sexual health, bladder/bowel, pain and psychosocial tools were evaluated. Several specific tools for human SCI studies have or are being developed to allow the more accurate determination for a clinically meaningful benefit (improvement in functional outcome or quality of life) being achieved as a result of a therapeutic intervention. Conclusion: Significant progress has been made, but further validation studies are required to identify the most appropriate tools for specific targets in a human SCI study or clinical trial.

KW - Diagnostic tools

KW - Functional assessment

KW - Outcome tools

KW - Quality of life and community participation

KW - Spinal cord clinical trial targets

KW - Upper and lower limb

UR - http://www.scopus.com/inward/record.url?scp=68349103190&partnerID=8YFLogxK

U2 - 10.1038/sc.2009.18

DO - 10.1038/sc.2009.18

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.systematicreview???

C2 - 19381157

AN - SCOPUS:68349103190

SN - 1362-4393

VL - 47

SP - 582

EP - 591

JO - Spinal Cord

JF - Spinal Cord

IS - 8

ER -

Outcome measures in spinal cord injury: Recent assessments and recommendations for future directions

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this