Organophosphate poisoning-induced acute renal failure

Yuval Cavari; Daniel Landau; Shaul Sofer; Tom Leibson; Isaac Lazar

doi:10.1097/PEC.0b013e31828e9e45

Organophosphate poisoning-induced acute renal failure

Yuval Cavari^*, Daniel Landau, Shaul Sofer, Tom Leibson, Isaac Lazar

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

BACKGROUND: Acute kidney injury as a direct complication of organophosphate poisoning has rarely been described and its etiology is unclear. CASE: A 17-year-old adolescent girl was admitted to the pediatric intensive care unit after a suicidal attempt with chlorpyrifos, an organophosphate insecticide compound. The patient developed acute kidney injury followed by renal failure, necessitating renal replacement therapy. She was treated with continuous venovenous hemofiltration with full resolution of her renal function. CONCLUSIONS: Organophosphate poisoning can lead to renal failure, which, with proper treatment, may be reversible but, if left unattended, might aggravate the clinical course of the disease. Physicians should be aware of this rare complication.

Original language	English
Pages (from-to)	646-647
Number of pages	2
Journal	Pediatric Emergency Care
Volume	29
Issue number	5
DOIs	https://doi.org/10.1097/PEC.0b013e31828e9e45
State	Published - May 2013
Externally published	Yes

Keywords

Chlorpyrifos
Continuous venovenous hemofiltration
Organophosphate intoxication
Renal failure

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10.1097/PEC.0b013e31828e9e45

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title = "Organophosphate poisoning-induced acute renal failure",

abstract = "BACKGROUND: Acute kidney injury as a direct complication of organophosphate poisoning has rarely been described and its etiology is unclear. CASE: A 17-year-old adolescent girl was admitted to the pediatric intensive care unit after a suicidal attempt with chlorpyrifos, an organophosphate insecticide compound. The patient developed acute kidney injury followed by renal failure, necessitating renal replacement therapy. She was treated with continuous venovenous hemofiltration with full resolution of her renal function. CONCLUSIONS: Organophosphate poisoning can lead to renal failure, which, with proper treatment, may be reversible but, if left unattended, might aggravate the clinical course of the disease. Physicians should be aware of this rare complication.",

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AU - Landau, Daniel

AU - Sofer, Shaul

AU - Leibson, Tom

AU - Lazar, Isaac

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N2 - BACKGROUND: Acute kidney injury as a direct complication of organophosphate poisoning has rarely been described and its etiology is unclear. CASE: A 17-year-old adolescent girl was admitted to the pediatric intensive care unit after a suicidal attempt with chlorpyrifos, an organophosphate insecticide compound. The patient developed acute kidney injury followed by renal failure, necessitating renal replacement therapy. She was treated with continuous venovenous hemofiltration with full resolution of her renal function. CONCLUSIONS: Organophosphate poisoning can lead to renal failure, which, with proper treatment, may be reversible but, if left unattended, might aggravate the clinical course of the disease. Physicians should be aware of this rare complication.

AB - BACKGROUND: Acute kidney injury as a direct complication of organophosphate poisoning has rarely been described and its etiology is unclear. CASE: A 17-year-old adolescent girl was admitted to the pediatric intensive care unit after a suicidal attempt with chlorpyrifos, an organophosphate insecticide compound. The patient developed acute kidney injury followed by renal failure, necessitating renal replacement therapy. She was treated with continuous venovenous hemofiltration with full resolution of her renal function. CONCLUSIONS: Organophosphate poisoning can lead to renal failure, which, with proper treatment, may be reversible but, if left unattended, might aggravate the clinical course of the disease. Physicians should be aware of this rare complication.

KW - Chlorpyrifos

KW - Continuous venovenous hemofiltration

KW - Organophosphate intoxication

KW - Renal failure

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Organophosphate poisoning-induced acute renal failure

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