Organ transplantation from a donor colonized with a multidrug-resistant organism: A case report

E. Goldberg, J. Bishara, S. Lev, P. Singer, J. Cohen

Research output: Contribution to journalArticlepeer-review

Abstract

The number of intensive care unit patients with infections caused by multidrug-resistant organisms is increasing in most developed countries. We report the case of a deceased multiorgan donor, who was an asymptomatic carrier of carbapenem-resistant Klebsiella pneumoniae (CR-KP) in the respiratory tract, a condition that was not diagnosed before organ harvesting and transplantation. The outcome of the 2 kidney recipients, the liver recipient, and 1 of the lung recipients was uneventful; in particular, no evidence of infection transmission or adverse graft outcomes was noted. The other lung recipient had a complicated postoperative course and, 4 weeks post transplantation, he developed a bacteremic pneumonia with CR-KP from which he subsequently died. These results suggest that, in well defined conditions, organs from donors who are CR-KP positive may be considered for transplantation.

Original languageEnglish
Pages (from-to)296-299
Number of pages4
JournalTransplant Infectious Disease
Volume14
Issue number3
DOIs
StatePublished - Jun 2012

Keywords

  • Carbapenem-resistant Klebsiella
  • Multidrug-resistant organisms
  • Solid organ transplantation

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