Oral solitary fibrous tumor: A retrospective clinico-pathological study and long-term follow-up

Tom Shmuly*, Yehonatan Ben Zvi, Gabriel Chaushu, Ilana Kaplan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background and Objectives: This was a retrospective single-center study to analyze and describe the clinical and histological features of all cases of oral solitary fibrous tumor (SFT). Study de-sign: the study included all consecutive cases of oral SFT diagnosed between 2008–2018 at a single tertiary center. Materials and Methods: Clinical data was retrieved from medical charts. The diagnosis of oral SFT was based upon the morphologic features of the lesions, in routine hematoxylin and eosin (H&E) stained sections and confirmed by immunohistochemical analyses including CD34, CD99, Bcl2, and stains for STAT6. Results: Seven cases of oral SFT were found. Of these, three (42%) were in males and four (58%) in females. The age range was 24–63 years (mean 47 ± 13). Four (58%) lesions were located in the buccal mucosa, two (28%) in the labial mucosa and one (14%) on the floor of the mouth. The diameter ranged between 3–50 mm (mean 22 ± 14 mm). All patients were treated with local excision. Follow-up periods were between 2–74 months (mean 41 ± 27). No recurrences were reported. Conclusions: We present a series of oral SFT, which were all non-aggressive in presentation and did not recur after conservative surgery (local excision) over a relatively long follow-up period.

Original languageEnglish
Article number152
Pages (from-to)1-9
Number of pages9
JournalMedicina (Lithuania)
Volume57
Issue number2
DOIs
StatePublished - Feb 2021

Keywords

  • CD34
  • Hemangiopericytoma
  • Immunohistochemistry
  • Oral cavity
  • Solitary fibrous tumor

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