Optimizing GC-MS for pharmaceutical and biochemical applications

Aviv Amirav, Alexander Fialkov, Alexander Gordin

Research output: Contribution to conferencePaperpeer-review

Abstract

The optimization of GC-MS for pharmaceutical and biochemical applications was discussed. The capability of thermally labile drugs and other biological compounds was increased with the use of a short column with very high column flow rate. A range of thermally labile drugs such as spectinomycene, tetracycline and reserpine was analyzed. Hyperthermal surface ionization was employed for achieving fast, sensitive and selective ionization of drugs in complex matrices such as drugs in raw urine, and drugs of abuse in a single human hair.

Original languageEnglish
Pages703
Number of pages1
StatePublished - 2002
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: 2 Jun 20026 Jun 2002

Conference

ConferenceProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Country/TerritoryUnited States
CityOrlando, FL
Period2/06/026/06/02

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