The optimization of GC-MS for pharmaceutical and biochemical applications was discussed. The capability of thermally labile drugs and other biological compounds was increased with the use of a short column with very high column flow rate. A range of thermally labile drugs such as spectinomycene, tetracycline and reserpine was analyzed. Hyperthermal surface ionization was employed for achieving fast, sensitive and selective ionization of drugs in complex matrices such as drugs in raw urine, and drugs of abuse in a single human hair.
|Number of pages||1|
|State||Published - 2002|
|Event||Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States|
Duration: 2 Jun 2002 → 6 Jun 2002
|Conference||Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics|
|Period||2/06/02 → 6/06/02|