TY - JOUR
T1 - Optic Nerve Head Changes After Intraocular Pressure-Lowering Glaucoma Surgeries Using Optical Coherence Tomography
AU - Silveira, Victoria D.Azevedo
AU - Lindenmeyer, Rodrigo Leivas
AU - Pakter, Helena Messinger
AU - Skaat, Alon
AU - Lavinsky, Daniel
AU - Oliveira, Monica
AU - Picceti, Egidio
AU - Lavinsky, Jaco
AU - De Arruda Mello, Paulo Augusto
AU - Lavinsky, Fabio
N1 - Publisher Copyright:
© 2023 Lippincott Williams and Wilkins. All rights reserved.
PY - 2023/9/1
Y1 - 2023/9/1
N2 - Précis: Optic nerve head (ONH) changes were detected with swept-source optical coherence tomography (SS-OCT) after intraocular pressure (IOP)-lowering glaucoma surgeries. Purpose: The aim of this study was to detect changes in the ONH with SS-OCT after IOP-lowering procedures. Patients and Methods: Patients with progressing glaucoma who were referred for IOP-lowering procedures were included. The participants underwent a 24-2 visual field test and SS-OCT (DRI OCT Triton Plus; Topcon). IOP and SS-OCT scans were obtained during the preoperative period and up to 7 days and 30-90 days postoperatively. ONH parameters were measured with a B-scan at the center of the optic disc and an average of 5 central B-scans. The hypotenuse of the ONH cup (HOC) was calculated using the Pythagorean theorem: hypotenuse2 = leg12 + leg22, considering the length and depth of the cup as the legs of a right triangle. We also evaluated changes in Bruch membrane opening (BMO)-to-BMO diameter. Statistical analysis was performed using generalized estimating equations. Results: A total of 15 eyes were included. The mean patient age was 70 (SD, 11.04) years. The mean circumpapillary retinal nerve fiber layer was 60.13 (SD, 23.21) µm and the visual field mean deviation was -13.29 (SD, 8.5) dB. The mean IOP at each visit was: 20.5 (SD, 4.99); 11 (SD, 4.95), and 15.7 (SD, 5.04), respectively. The mean HOC, the mean depth and length of the ONH cup, and the BMO-to-BMO diameter decreased significantly after the IOP-lowering procedures. Conclusions: The HOC evaluated with SS-OCT significantly decreased after IOP-lowering surgeries. This parameter was useful for evaluating short-term changes in the ONH.
AB - Précis: Optic nerve head (ONH) changes were detected with swept-source optical coherence tomography (SS-OCT) after intraocular pressure (IOP)-lowering glaucoma surgeries. Purpose: The aim of this study was to detect changes in the ONH with SS-OCT after IOP-lowering procedures. Patients and Methods: Patients with progressing glaucoma who were referred for IOP-lowering procedures were included. The participants underwent a 24-2 visual field test and SS-OCT (DRI OCT Triton Plus; Topcon). IOP and SS-OCT scans were obtained during the preoperative period and up to 7 days and 30-90 days postoperatively. ONH parameters were measured with a B-scan at the center of the optic disc and an average of 5 central B-scans. The hypotenuse of the ONH cup (HOC) was calculated using the Pythagorean theorem: hypotenuse2 = leg12 + leg22, considering the length and depth of the cup as the legs of a right triangle. We also evaluated changes in Bruch membrane opening (BMO)-to-BMO diameter. Statistical analysis was performed using generalized estimating equations. Results: A total of 15 eyes were included. The mean patient age was 70 (SD, 11.04) years. The mean circumpapillary retinal nerve fiber layer was 60.13 (SD, 23.21) µm and the visual field mean deviation was -13.29 (SD, 8.5) dB. The mean IOP at each visit was: 20.5 (SD, 4.99); 11 (SD, 4.95), and 15.7 (SD, 5.04), respectively. The mean HOC, the mean depth and length of the ONH cup, and the BMO-to-BMO diameter decreased significantly after the IOP-lowering procedures. Conclusions: The HOC evaluated with SS-OCT significantly decreased after IOP-lowering surgeries. This parameter was useful for evaluating short-term changes in the ONH.
KW - diagnostic techniques
KW - glaucoma surgery
KW - optic nerve
KW - optical coherence tomography
UR - http://www.scopus.com/inward/record.url?scp=85169173992&partnerID=8YFLogxK
U2 - 10.1097/IJG.0000000000002242
DO - 10.1097/IJG.0000000000002242
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C2 - 37311019
AN - SCOPUS:85169173992
SN - 1057-0829
VL - 32
SP - 756
EP - 761
JO - Journal of Glaucoma
JF - Journal of Glaucoma
IS - 9
ER -