Optic Nerve Head Changes After Intraocular Pressure-Lowering Glaucoma Surgeries Using Optical Coherence Tomography

Victoria D.Azevedo Silveira, Rodrigo Leivas Lindenmeyer, Helena Messinger Pakter, Alon Skaat, Daniel Lavinsky, Monica Oliveira, Egidio Picceti, Jaco Lavinsky, Paulo Augusto De Arruda Mello, Fabio Lavinsky*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Précis: Optic nerve head (ONH) changes were detected with swept-source optical coherence tomography (SS-OCT) after intraocular pressure (IOP)-lowering glaucoma surgeries. Purpose: The aim of this study was to detect changes in the ONH with SS-OCT after IOP-lowering procedures. Patients and Methods: Patients with progressing glaucoma who were referred for IOP-lowering procedures were included. The participants underwent a 24-2 visual field test and SS-OCT (DRI OCT Triton Plus; Topcon). IOP and SS-OCT scans were obtained during the preoperative period and up to 7 days and 30-90 days postoperatively. ONH parameters were measured with a B-scan at the center of the optic disc and an average of 5 central B-scans. The hypotenuse of the ONH cup (HOC) was calculated using the Pythagorean theorem: hypotenuse2 = leg12 + leg22, considering the length and depth of the cup as the legs of a right triangle. We also evaluated changes in Bruch membrane opening (BMO)-to-BMO diameter. Statistical analysis was performed using generalized estimating equations. Results: A total of 15 eyes were included. The mean patient age was 70 (SD, 11.04) years. The mean circumpapillary retinal nerve fiber layer was 60.13 (SD, 23.21) µm and the visual field mean deviation was -13.29 (SD, 8.5) dB. The mean IOP at each visit was: 20.5 (SD, 4.99); 11 (SD, 4.95), and 15.7 (SD, 5.04), respectively. The mean HOC, the mean depth and length of the ONH cup, and the BMO-to-BMO diameter decreased significantly after the IOP-lowering procedures. Conclusions: The HOC evaluated with SS-OCT significantly decreased after IOP-lowering surgeries. This parameter was useful for evaluating short-term changes in the ONH.

Original languageEnglish
Pages (from-to)756-761
Number of pages6
JournalJournal of Glaucoma
Issue number9
StatePublished - 1 Sep 2023


  • diagnostic techniques
  • glaucoma surgery
  • optic nerve
  • optical coherence tomography


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