TY - JOUR
T1 - One-Year Follow-Up of Advanced Hybrid Closed-Loop System in Adults with Type 1 Diabetes Previously Naive to Diabetes Technology
T2 - The Effect of Switching to a Calibration-Free Sensor
AU - Matejko, Bartlomiej
AU - Juza, Anna
AU - Kieć-Wilk, Beata
AU - Cyranka, Katarzyna
AU - Krzyzowska, Sabina
AU - Cohen, Ohad
AU - Malecki, Maciej T.
AU - Klupa, Tomasz
N1 - Publisher Copyright:
© Mary Ann Liebert, Inc.
PY - 2023/8/1
Y1 - 2023/8/1
N2 - The aim of this study was to observe the 1-year clinical outcomes of people with type 1 diabetes who switched from multiple daily injection + blood glucose meter to an advanced hybrid closed-loop (AHCL) system (Medtronic MiniMed™ 780G system [MM 780G]). In addition, the effect of changing at month 6 to a calibration-free sensor (Guardian™ 4 Sensor [G4S]) was evaluated. Eighteen participants (10 men, age 40.9 ± 7.6 years) completed 1 year of MM 780G use. Time in range (TIR; 70-180 mg/dL) remained stable and ranged from 83.2% in month 9 to 84.8% in month 3. There was no difference between TIR at 3 months before switching versus 3 months after switching to G4S (P = 0.614). AHCL system in adults significantly improves glycemic outcomes. This improved glycemic control was maintained over the 12 months. Switching to a calibration-free sensor (G4S) did not affect outcomes but required less patient involvement.
AB - The aim of this study was to observe the 1-year clinical outcomes of people with type 1 diabetes who switched from multiple daily injection + blood glucose meter to an advanced hybrid closed-loop (AHCL) system (Medtronic MiniMed™ 780G system [MM 780G]). In addition, the effect of changing at month 6 to a calibration-free sensor (Guardian™ 4 Sensor [G4S]) was evaluated. Eighteen participants (10 men, age 40.9 ± 7.6 years) completed 1 year of MM 780G use. Time in range (TIR; 70-180 mg/dL) remained stable and ranged from 83.2% in month 9 to 84.8% in month 3. There was no difference between TIR at 3 months before switching versus 3 months after switching to G4S (P = 0.614). AHCL system in adults significantly improves glycemic outcomes. This improved glycemic control was maintained over the 12 months. Switching to a calibration-free sensor (G4S) did not affect outcomes but required less patient involvement.
KW - Advanced hybrid closed-loop system
KW - Calibration-free sensor
KW - Type 1 diabetes
UR - http://www.scopus.com/inward/record.url?scp=85166386440&partnerID=8YFLogxK
U2 - 10.1089/dia.2023.0059
DO - 10.1089/dia.2023.0059
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 37184526
AN - SCOPUS:85166386440
SN - 1520-9156
VL - 25
SP - 554
EP - 558
JO - Diabetes Technology and Therapeutics
JF - Diabetes Technology and Therapeutics
IS - 8
ER -