One-Year Follow-Up of Advanced Hybrid Closed-Loop System in Adults with Type 1 Diabetes Previously Naive to Diabetes Technology: The Effect of Switching to a Calibration-Free Sensor

Bartlomiej Matejko*, Anna Juza, Beata Kieć-Wilk, Katarzyna Cyranka, Sabina Krzyzowska, Ohad Cohen, Maciej T. Malecki, Tomasz Klupa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The aim of this study was to observe the 1-year clinical outcomes of people with type 1 diabetes who switched from multiple daily injection + blood glucose meter to an advanced hybrid closed-loop (AHCL) system (Medtronic MiniMed™ 780G system [MM 780G]). In addition, the effect of changing at month 6 to a calibration-free sensor (Guardian™ 4 Sensor [G4S]) was evaluated. Eighteen participants (10 men, age 40.9 ± 7.6 years) completed 1 year of MM 780G use. Time in range (TIR; 70-180 mg/dL) remained stable and ranged from 83.2% in month 9 to 84.8% in month 3. There was no difference between TIR at 3 months before switching versus 3 months after switching to G4S (P = 0.614). AHCL system in adults significantly improves glycemic outcomes. This improved glycemic control was maintained over the 12 months. Switching to a calibration-free sensor (G4S) did not affect outcomes but required less patient involvement.

Original languageEnglish
Pages (from-to)554-558
Number of pages5
JournalDiabetes Technology and Therapeutics
Volume25
Issue number8
DOIs
StatePublished - 1 Aug 2023
Externally publishedYes

Funding

FundersFunder number
MedtronicERP-2019-12000

    Keywords

    • Advanced hybrid closed-loop system
    • Calibration-free sensor
    • Type 1 diabetes

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