On the distribution of the nucleotides in the seven completely sequenced DNAs

Camil Fuchs

doi:10.1016/0378-1119(80)90157-2

On the distribution of the nucleotides in the seven completely sequenced DNAs

Camil Fuchs^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Several Markov chain models (up to fourth order) have been fitted to the sequences of the seven DNAs presented in Fuchs et al. (1980). Two methods for determining the order of Markov chain are applied to the data. The two methods lead to different conclusions and we dicuss these discrepancies. When the distribution of the nucleotides in a DNA sequence is investigated, it is suggested that the study on the order of the Markov model should be supplemented with additional analysis.

Original language	English
Pages (from-to)	371-373
Number of pages	3
Journal	Gene
Volume	10
Issue number	4
DOIs	https://doi.org/10.1016/0378-1119(80)90157-2
State	Published - 1980
Externally published	Yes

Keywords

Akaike information criterion
DNA
Markov chains
Recombinant
SV40
bacteriophage
likelihood-ratio tests
pA03
plasmids pBR322
probability models
virus
φX174, G4, fd, M13

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10.1016/0378-1119(80)90157-2

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AB - Several Markov chain models (up to fourth order) have been fitted to the sequences of the seven DNAs presented in Fuchs et al. (1980). Two methods for determining the order of Markov chain are applied to the data. The two methods lead to different conclusions and we dicuss these discrepancies. When the distribution of the nucleotides in a DNA sequence is investigated, it is suggested that the study on the order of the Markov model should be supplemented with additional analysis.

KW - Akaike information criterion

KW - DNA

KW - Markov chains

KW - Recombinant

KW - SV40

KW - bacteriophage

KW - likelihood-ratio tests

KW - pA03

KW - plasmids pBR322

KW - probability models

KW - virus

KW - φX174, G4, fd, M13

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JO - Gene

JF - Gene

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ER -

On the distribution of the nucleotides in the seven completely sequenced DNAs

Abstract

Keywords

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