On chiasma formation point processes having the count location property

Uri Liberman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The count-location (C-L) chiasma formation schemes introduced by Karlin and Liberman (1979b) encompass a broad class of map functions involving positive, negative or no chiasma interference. The C-L schemes do not explictly assume a specific mechanism of crossover formation, but rather a statistical property of the process. If viewed as a stochastic point process along the chromosome, it is shown that a crossing over mechanism having the C-L property is actually a rescaled mixture of Poisson processes. Surprisingly it turns out that these C-L point processes involve negative interference throughout the entire genome.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalJournal of Mathematical Biology
Volume21
Issue number1
DOIs
StatePublished - Dec 1984

Funding

FundersFunder number
National Institute of General Medical SciencesR01GM028016

    Keywords

    • Chiasma formation
    • interference
    • point process

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