TY - JOUR
T1 - On averages and peaks
T2 - How do people integrate attitudes about multiple diseases to reach a decision about multiplex genetic testing?
AU - Shiloh, Shoshana
AU - Wade, Christopher H.
AU - Roberts, J. Scott
AU - Hensley Alford, Sharon
AU - Biesecker, Barbara B.
N1 - Funding Information:
This research was supported by the Intramural Research Program of the National Human Genome Research Institute, National Institutes of Health. The research was made possible through a collaboration with the Cancer Research Network funded by the National Cancer Institute (U19CA 079689). Group Health Research Institute and Henry Ford Hospital provided additional resources. Genotyping services were provided by the Center for Inherited Disease Research (CIDR). CIDR is fully funded through a federal contract from the National Institutes of Health to The Johns Hopkins University (HHSN268200782096C). In addition, this research was supported in part by an appointment to the Senior Fellowship Program at the National Institutes of Health. This program is administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the US Department of Energy and the National Institutes of Health.
PY - 2013/1
Y1 - 2013/1
N2 - Background. The aim of the current study was to learn how people integrate attitudes about multiple health conditions to make a decision about genetic testing uptake. Methods. This study recruited 294 healthy young adults from a parent research project, the Multiplex Initiative, conducted in a large health care system in Detroit, Michigan. All participants were offered a multiplex genetic test that assessed risk for 8 common health conditions (e.g., type 2 diabetes). Data were collected from a baseline survey, a web-based survey, and at the time of testing. Results. Averaging attitudes across diseases predicted test uptake but did not contribute beyond peak attitudes, the highest attitude toward testing for a single disease in the set. Peak attitudes were found sufficient to predict test uptake. Limitations. The effects of set size and mode of presentation could not be examined because these factors were constant in the multiplex test offered. Conclusions. These findings support theories suggesting that people use representative evaluations in attitude formation. The implication of these findings for further developments in genetic testing is that the communication and impact of multiplex testing may need to be considered in the light of a bias toward peak attitudes.
AB - Background. The aim of the current study was to learn how people integrate attitudes about multiple health conditions to make a decision about genetic testing uptake. Methods. This study recruited 294 healthy young adults from a parent research project, the Multiplex Initiative, conducted in a large health care system in Detroit, Michigan. All participants were offered a multiplex genetic test that assessed risk for 8 common health conditions (e.g., type 2 diabetes). Data were collected from a baseline survey, a web-based survey, and at the time of testing. Results. Averaging attitudes across diseases predicted test uptake but did not contribute beyond peak attitudes, the highest attitude toward testing for a single disease in the set. Peak attitudes were found sufficient to predict test uptake. Limitations. The effects of set size and mode of presentation could not be examined because these factors were constant in the multiplex test offered. Conclusions. These findings support theories suggesting that people use representative evaluations in attitude formation. The implication of these findings for further developments in genetic testing is that the communication and impact of multiplex testing may need to be considered in the light of a bias toward peak attitudes.
KW - cognitive psychology
KW - judgment and decision psychology
KW - patient choice modeling
KW - social judgment theory
UR - http://www.scopus.com/inward/record.url?scp=84872363364&partnerID=8YFLogxK
U2 - 10.1177/0272989X12464432
DO - 10.1177/0272989X12464432
M3 - מאמר
C2 - 23128581
AN - SCOPUS:84872363364
VL - 33
SP - 71
EP - 77
JO - Medical Decision Making
JF - Medical Decision Making
SN - 0272-989X
IS - 1
ER -