TY - JOUR
T1 - Omriolide A and B; Two new rearranged spongian diterpenes from the marine sponge Dictyodendrilla aff. retiara
AU - Rudi, Amira
AU - Erez, Yuval
AU - Benayahu, Yehuda
AU - Kashman, Yoel
N1 - Funding Information:
We thank PharmaMar Madrid for financial support and Professor R. van Soest for the identification of the sponge.
PY - 2005/12/5
Y1 - 2005/12/5
N2 - Two new rearranged spongian diterpenes designated omriolide A and B were isolated from the southern Kenyan sponge Dictyodendrilla aff. retiara collected at Wasini Is., Shimoni Channel. Omriolide A possesses an octalin linked to a unique trioxatricyclo[5.2.1.04,10]decane ring system, forming a tricyclic 'cap'. Omriolide B comprised a tricyclo[5.4.0.02,4]undecane linked to a dioxabicyclo[3.3.0]octane. The structures of both diterpenes were elucidated by interpretation of MS results and, mainly, 1D and 2D NMR spectra.
AB - Two new rearranged spongian diterpenes designated omriolide A and B were isolated from the southern Kenyan sponge Dictyodendrilla aff. retiara collected at Wasini Is., Shimoni Channel. Omriolide A possesses an octalin linked to a unique trioxatricyclo[5.2.1.04,10]decane ring system, forming a tricyclic 'cap'. Omriolide B comprised a tricyclo[5.4.0.02,4]undecane linked to a dioxabicyclo[3.3.0]octane. The structures of both diterpenes were elucidated by interpretation of MS results and, mainly, 1D and 2D NMR spectra.
KW - Rearranged spongian diterpenes
KW - Trioxatricyclo[5.2.1.0]octane heterocycle
UR - http://www.scopus.com/inward/record.url?scp=27644560643&partnerID=8YFLogxK
U2 - 10.1016/j.tetlet.2005.09.047
DO - 10.1016/j.tetlet.2005.09.047
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AN - SCOPUS:27644560643
SN - 0040-4039
VL - 46
SP - 8613
EP - 8616
JO - Tetrahedron Letters
JF - Tetrahedron Letters
IS - 49
ER -