TY - JOUR
T1 - Olfactory sensitivity in major depressive disorder and obsessive compulsive disorder
AU - Gross-Isseroff, Ruth
AU - Luca-Haimovici, Keren
AU - Sasson, Yehuda
AU - Kindler, Seth
AU - Kotler, Moshe
AU - Zohar, Joseph
PY - 1994/5/15
Y1 - 1994/5/15
N2 - Olfactory sensitivity to two odorants, isoamyl acetate and androstenone, was assessed in 14 obsessive compulsive disorder (OCD) patients, nine major depressive disorder (MDD) patients, and 16 sex- and age-matched healthy controls. Tests were performed during a drug-free period, and 3 and 6 weeks after initiation of antidepressant drug therapy. No difference in olfactory sensitivity, to either odorant, was found between OCD patientsand controls at any time. In MDD patients, a significant increase in the sensitivity to isoamyl acetate was observed 6 weeks after initiation of treatment, compared to controls.
AB - Olfactory sensitivity to two odorants, isoamyl acetate and androstenone, was assessed in 14 obsessive compulsive disorder (OCD) patients, nine major depressive disorder (MDD) patients, and 16 sex- and age-matched healthy controls. Tests were performed during a drug-free period, and 3 and 6 weeks after initiation of antidepressant drug therapy. No difference in olfactory sensitivity, to either odorant, was found between OCD patientsand controls at any time. In MDD patients, a significant increase in the sensitivity to isoamyl acetate was observed 6 weeks after initiation of treatment, compared to controls.
KW - Olfactory thresholds, obsessive compulsive disorder
KW - androstenone
KW - isoamyl acetate
KW - major depressive disorder
UR - https://www.scopus.com/pages/publications/0028276084
U2 - 10.1016/0006-3223(94)91142-8
DO - 10.1016/0006-3223(94)91142-8
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AN - SCOPUS:0028276084
SN - 0006-3223
VL - 35
SP - 798
EP - 802
JO - Biological Psychiatry
JF - Biological Psychiatry
IS - 10
ER -