Olfactory dysfunction and autoimmunity: Pathogenesis and new insights

Oded Shamriz*, Yehuda Shoenfeld

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Olfaction plays an important role in the perception of our environment. Smell impairment is known to be a manifestation of several autoimmune diseases. Similarities between the olfactory and immune systems and previously published human studies and animal models of autoimmune diseases account for the accumulating evidence for this observation. In this review, we will present the current literature concerning olfactory dysfunction in autoimmune diseases, discuss clinical aspects and provide new insights regarding pathogenesis and possible mechanisms.

Original languageEnglish
Pages (from-to)1037-1042
Number of pages6
JournalClinical and Experimental Rheumatology
Issue number6
StatePublished - 1 Nov 2017
Externally publishedYes


  • Autoimmune diseases
  • Autoimmunity
  • Olfaction
  • Olfactory system
  • Smell


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