Abstract
Ofloxacin can cause retarded ossification and arthropathy in young animals, but there is no published information about its teratogenicity in humans. A 36-year-old woman was treated with ofloxacin 200 mg bid for 6 days during the 19th week of gestation. Ultrasound follow-up of the measurements and structure of the fetal long bones revealed no abnormalities. The neonate's physical examination and X-rays of the chest and long bones were normal. Although no teratogenic or toxic effects were observed in this patient, the use of ofloxacin in human pregnancy should only be a clinical consideration until sufficient evidence regarding its safety in the human fetus has been published.
Original language | English |
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Pages (from-to) | 1181-1182 |
Number of pages | 2 |
Journal | Annals of Pharmacotherapy |
Volume | 25 |
Issue number | 11 |
DOIs |
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State | Published - Nov 1991 |