Ophthalmological investigations of untreated Laron syndrome patients revealed retarded growth of the ocular globe. The shorter anterior length of the anterior chamber was normalized by IGF-I treatment. The retinal vascularization was reduced as were the number of tortuosities of the arteries. Two patients with diabetes mellitus developed retinal neovascularization.
|Title of host publication||Laron Syndrome - From Man to Mouse|
|Subtitle of host publication||Lessons from Clinical and Experimental Experience|
|Publisher||Springer Berlin Heidelberg|
|Number of pages||8|
|State||Published - 2011|