Ocular central nervous system lymphoma mimicking choroidal neovascularization

Shiri Zayit-Soudry*, Anat Kesler, Jonathan Tsehori, Leonor Leider-Trejo, Anat Loewenstein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Two patients evaluated for metamorphopsia were noted to have inferotemporal retinal pigment epithelium elevations formed by a yellowish lesion. Fluorescein angiography showed granular hyperfluorescence with late leakage, which was interpreted as an occult choroidal neovascularization. One patient underwent photodynamic therapy. In both patients, neither vitreous cells nor neurologic manifestations were evident on presentation. Subsequent neurological signs appeared that prompted performance of brain imaging, which confirmed a space-occupying lesion. In both patients, the tumor was proven on histopathologic examination of brain tissue to be central nervous system lymphoma. Awareness of other possible underlying pathologies is warranted in cases of atypical choroidal neovascularization.

Original languageEnglish
Pages (from-to)146-149
Number of pages4
JournalOphthalmic Surgery Lasers and Imaging
Issue number2
StatePublished - Mar 2008


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